32d cells Search Results


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Myelo Therapeutics GmbH 32d-gen cell lines
32d Gen Cell Lines, supplied by Myelo Therapeutics GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Lonza nucleofector kits for 32d cells
Nucleofector Kits For 32d Cells, supplied by Lonza, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Quelle GmbH cell line 32d-bcl-2
Cell Line 32d Bcl 2, supplied by Quelle GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Altor BioScience 32d-il-2/15rβ (32dβ) cells
32d Il 2/15rβ (32dβ) Cells, supplied by Altor BioScience, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Multiplexion GmbH 32d cells
32d Cells, supplied by Multiplexion GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Quelle GmbH 32d murine myeloid cell line overexpressing bcl-xl
32d Murine Myeloid Cell Line Overexpressing Bcl Xl, supplied by Quelle GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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China Center for Type Culture Collection mouse 32d cells
Mouse 32d Cells, supplied by China Center for Type Culture Collection, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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BioResource International Inc 32d cells
32d Cells, supplied by BioResource International Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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clea japan inc gene-modified 32d cell lines
iPAI-1 protects chronic myeloid leukemia cells from tyrosine kinase inhibitor treatment. (A) A representative flow cytometric profile for intracellular plasminogen activator inhibitor-1 (iPAI-1) expressions in PAI-1-overexpression (PAI-1 OE), PAI-1-knockdown (PAI-1 KD), or wild-type parental <t>32D</t> p210 cells (PAI-1 WT). (B) Representative flow cytometric profiles and percentage of Annexin V + /PI + population in PAI-1 OE, PAI-1 KD, or PAI-1 WT cells before imatinib (Pre-IM) and after imatinib (Post-IM) treatment in vitro (n=6). (C) Schema for in vivo experiments. (D) Representative flow cytometric profiles and percentages of leukemic cells in the bone marrow (BM) (n=7). Data represent means ± standard deviation. Statistical significance was determined by Mann-Whitney unpaired t -test. P <0.001, by a Kruskal-Wallis test. GFP: green fluorescent protein.
Gene Modified 32d Cell Lines, supplied by clea japan inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Quelle GmbH 32d.3 cells expressing epor and various mutant epors
iPAI-1 protects chronic myeloid leukemia cells from tyrosine kinase inhibitor treatment. (A) A representative flow cytometric profile for intracellular plasminogen activator inhibitor-1 (iPAI-1) expressions in PAI-1-overexpression (PAI-1 OE), PAI-1-knockdown (PAI-1 KD), or wild-type parental <t>32D</t> p210 cells (PAI-1 WT). (B) Representative flow cytometric profiles and percentage of Annexin V + /PI + population in PAI-1 OE, PAI-1 KD, or PAI-1 WT cells before imatinib (Pre-IM) and after imatinib (Post-IM) treatment in vitro (n=6). (C) Schema for in vivo experiments. (D) Representative flow cytometric profiles and percentages of leukemic cells in the bone marrow (BM) (n=7). Data represent means ± standard deviation. Statistical significance was determined by Mann-Whitney unpaired t -test. P <0.001, by a Kruskal-Wallis test. GFP: green fluorescent protein.
32d.3 Cells Expressing Epor And Various Mutant Epors, supplied by Quelle GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Johns Hopkins HealthCare 32d clone no. 13 cells
iPAI-1 protects chronic myeloid leukemia cells from tyrosine kinase inhibitor treatment. (A) A representative flow cytometric profile for intracellular plasminogen activator inhibitor-1 (iPAI-1) expressions in PAI-1-overexpression (PAI-1 OE), PAI-1-knockdown (PAI-1 KD), or wild-type parental <t>32D</t> p210 cells (PAI-1 WT). (B) Representative flow cytometric profiles and percentage of Annexin V + /PI + population in PAI-1 OE, PAI-1 KD, or PAI-1 WT cells before imatinib (Pre-IM) and after imatinib (Post-IM) treatment in vitro (n=6). (C) Schema for in vivo experiments. (D) Representative flow cytometric profiles and percentages of leukemic cells in the bone marrow (BM) (n=7). Data represent means ± standard deviation. Statistical significance was determined by Mann-Whitney unpaired t -test. P <0.001, by a Kruskal-Wallis test. GFP: green fluorescent protein.
32d Clone No. 13 Cells, supplied by Johns Hopkins HealthCare, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Genesis Research and Development 32d clone 23 cells
iPAI-1 protects chronic myeloid leukemia cells from tyrosine kinase inhibitor treatment. (A) A representative flow cytometric profile for intracellular plasminogen activator inhibitor-1 (iPAI-1) expressions in PAI-1-overexpression (PAI-1 OE), PAI-1-knockdown (PAI-1 KD), or wild-type parental <t>32D</t> p210 cells (PAI-1 WT). (B) Representative flow cytometric profiles and percentage of Annexin V + /PI + population in PAI-1 OE, PAI-1 KD, or PAI-1 WT cells before imatinib (Pre-IM) and after imatinib (Post-IM) treatment in vitro (n=6). (C) Schema for in vivo experiments. (D) Representative flow cytometric profiles and percentages of leukemic cells in the bone marrow (BM) (n=7). Data represent means ± standard deviation. Statistical significance was determined by Mann-Whitney unpaired t -test. P <0.001, by a Kruskal-Wallis test. GFP: green fluorescent protein.
32d Clone 23 Cells, supplied by Genesis Research and Development, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


iPAI-1 protects chronic myeloid leukemia cells from tyrosine kinase inhibitor treatment. (A) A representative flow cytometric profile for intracellular plasminogen activator inhibitor-1 (iPAI-1) expressions in PAI-1-overexpression (PAI-1 OE), PAI-1-knockdown (PAI-1 KD), or wild-type parental 32D p210 cells (PAI-1 WT). (B) Representative flow cytometric profiles and percentage of Annexin V + /PI + population in PAI-1 OE, PAI-1 KD, or PAI-1 WT cells before imatinib (Pre-IM) and after imatinib (Post-IM) treatment in vitro (n=6). (C) Schema for in vivo experiments. (D) Representative flow cytometric profiles and percentages of leukemic cells in the bone marrow (BM) (n=7). Data represent means ± standard deviation. Statistical significance was determined by Mann-Whitney unpaired t -test. P <0.001, by a Kruskal-Wallis test. GFP: green fluorescent protein.

Journal: Haematologica

Article Title: Targeting of plasminogen activator inhibitor-1 activity promotes elimination of chronic myeloid leukemia stem cells

doi: 10.3324/haematol.2019.230227

Figure Lengend Snippet: iPAI-1 protects chronic myeloid leukemia cells from tyrosine kinase inhibitor treatment. (A) A representative flow cytometric profile for intracellular plasminogen activator inhibitor-1 (iPAI-1) expressions in PAI-1-overexpression (PAI-1 OE), PAI-1-knockdown (PAI-1 KD), or wild-type parental 32D p210 cells (PAI-1 WT). (B) Representative flow cytometric profiles and percentage of Annexin V + /PI + population in PAI-1 OE, PAI-1 KD, or PAI-1 WT cells before imatinib (Pre-IM) and after imatinib (Post-IM) treatment in vitro (n=6). (C) Schema for in vivo experiments. (D) Representative flow cytometric profiles and percentages of leukemic cells in the bone marrow (BM) (n=7). Data represent means ± standard deviation. Statistical significance was determined by Mann-Whitney unpaired t -test. P <0.001, by a Kruskal-Wallis test. GFP: green fluorescent protein.

Article Snippet: Another set of experiments, gene-modified 32D cell lines were also transplanted into non-irradiated C3H/HeNCrl mice (CLEA Japan).

Techniques: Over Expression, In Vitro, In Vivo, Standard Deviation, MANN-WHITNEY